Zinedine Zidane will be without Luka Modric and Gareth Bale for Tuesday's Champions League tie against Galatasaray in Istanbul.
Madrid travel to Turkey in desperate need of a win to kick start their European campaign after losing to Paris Saint-Germain and drawing with Club Brugge.
Modric and Bale both missed the loss to Mallorca at the weekend and neither has recovered in time for the vital match against Galatasaray this week.
However, Eden Hazard does return to the squad following the birth of his fourth child, while Toni Kroos and Dani Carvajal are also back.
The full squad is:
Goalkeepers: Courtois, Areola & Altube.
Defenders: Carvajal, Militão, Ramos, Varane, Marcelo, Odriozola & Mendy.
Midfielders: Kroos, Casemiro, Valverde, James & Isco.
Forwards: Hazard, Benzema, Jović, Brahim, Vinicius Jr. & Rodrygo.